Equal masses of fat are mixed with equal lipase concentrations at 37 °C. A has large droplets at pH 3; B has large droplets at pH 8; C has small droplets at pH 8. This lipase works best near pH 8.
.1
Explain why B should digest fat faster than A.
[2 marks]
.2
Explain why C should be faster than B and relate this to bile.
[2 marks]
4 marksFoundation and Higher4.2.2.5 Health issues
AQA Trilogy 8464
Spec and skills
Paper scope: B1
Spec 4.2.2.5
Original practice question
Answer and supported method checks
A virus damages immune cells. Patients later get frequent infections from other pathogens. Long illness prevents some patients from working or meeting friends.
.1
Explain why other infections become more frequent.
[2 marks]
.2
Suggest two links between long illness and poorer mental health.
[2 marks]
6 marksHigher4.3.1.7 Vaccination
AQA Trilogy 8464
Spec and skills
Paper scope: B1
Spec 4.3.1.7
Original practice question
Answer and supported method checks
A town offers a vaccine against a serious droplet-spread disease. Some residents cannot receive it for medical reasons. A group argues that vaccination is purely an individual choice with no effect on other people.
Evaluate the group's claim using vaccination and transmission.
[6 marks]
4 marksFoundation and Higher4.3.1.9 Discovery and development of drugs
AQA Trilogy 8464
Spec and skills
Paper scope: B1
Spec 4.3.1.9
Original practice question
Answer and supported method checks
In a trial of a new cream, 84 of 140 treated patients improve. In an identical placebo group, 56 of 140 improve.
.1
Calculate the difference in improvement rates in percentage points.
[2 marks]
.2
Evaluate the conclusion that the cream cures every user.
[2 marks]
6 marksFoundation and HigherRequired practical 054.4.1.2 Rate of photosynthesis
AQA Trilogy 8464
Spec and skills
Paper scope: B1
Spec 4.4.1.2
Original practice question
Answer and supported method checks
A class plans to investigate how light intensity affects photosynthesis using pondweed, a lamp, a ruler, a water bath and a gas-collection syringe.
Plan an investigation that produces valid, repeatable rate comparisons.