GCSE Combined Science revision · Biology: cells, organisation and disease

Defences, vaccines and antibiotics

The idea

Malaria is caused by a protist carried by mosquitoes. The body's non-specific defences include the skin, nose hairs, mucus and cilia in the trachea, and stomach acid. White blood cells engulf pathogens (phagocytosis), produce antibodies and produce antitoxins. Vaccination injects a dead or inactive pathogen so white blood cells can make antibodies quickly if the real pathogen enters. Antibiotics kill bacteria; painkillers only treat symptoms.

  1. Name the defence and how it works.
  2. Explain vaccination in steps.
  3. Separate antibiotics (cure bacterial infections) from painkillers (symptoms).

Watch out Antibiotics kill bacteria inside the body but have no effect on viruses.

See it worked

Worked example

Explain how vaccination protects a person against a disease.

  1. A dead or inactive form of the pathogen is injected.
  2. White blood cells make antibodies against it.
  3. If the real pathogen enters, antibodies are made quickly, preventing illness.

Answer The body learns to make the right antibodies quickly

Your turn

Question 1Calculator allowed1 mark

What causes malaria?

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Question 2Calculator allowed1 mark

Which is a function of white blood cells?

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Question 3Calculator allowed1 mark

Why are antibiotics not used to treat flu?

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In past papers

55 official questions in 41 papers since 2018. The latest:

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Independent practice for AQA GCSE Combined Science: Trilogy (8464), not endorsed by AQA.

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